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An ENU-Induced Mutation in the Mertk Gene (Mertk(nmf12)) Leads to a Slow Form of Retinal Degeneration
PURPOSE. To determine the basis and to characterize the phenotype of a chemically induced mutation in a mouse model of retinal degeneration. METHODS. Screening by indirect ophthalmoscopy identified a line of N-ethyl-N-nitrosourea (ENU) mutagenized mice demonstrating retinal patches. Longitudinal stu...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Association for Research in Vision and Ophthalmology, Inc.
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3175976/ https://ncbi.nlm.nih.gov/pubmed/21436282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-7077 |
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