Sphingolipid profile alters in retinal dystrophic P23H-1 rats and systemic FTY720 can delay retinal degeneration

Retinal degeneration (RD) affects millions of people and is a major cause of ocular impairment and blindness. With a wide range of mutations and conditions leading to degeneration, targeting downstream processes is necessary for developing effective treatments. Ceramide and sphingosine-1-phosphate,...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Stiles, Megan, Qi, Hui, Sun, Eleanor, Tan, Jeremy, Porter, Hunter, Allegood, Jeremy, Chalfant, Charles E., Yasumura, Douglas, Matthes, Michael T., LaVail, Matthew M., Mandal, Nawajes A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847629/
https://ncbi.nlm.nih.gov/pubmed/26947037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M063719
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