Mechanisms of Chemoresistance in Malignant Glioma

Por Sarkaria, Jann N., Kitange, Gaspar J., James, C. David, Plummer, Ruth, Calvert, Hilary, Weller, Michael, Wick, Wolfgang
Publicado em 2008

Induction of MGMT expression is associated with temozolomide resistance in glioblastoma xenografts

Por Kitange, Gaspar J., Carlson, Brett L., Schroeder, Mark A., Grogan, Patrick T., Lamont, Jeff D., Decker, Paul A., Wu, Wenting, James, C. David, Sarkaria, Jann N.
Publicado em 2009

Expression of CD74 in high Grade Gliomas: A Potential Role in Temozolomide Resistance

Por Kitange, Gaspar J., Carlson, Brett L., Schroeder, Mark A., Decker, Paul A., Morlan, Bruce W., Wu, Wenting, Ballman, Karla V., Giannini, Caterina, Sarkaria, Jann N.
Publicado em 2010

Radiosensitizing effects of TMZ observed in vivo only in a subset of MGMT methylated GBM xenografts

Por Carlson, Brett L., Grogan, Patrick T., Mladek, Ann C., Schroeder, Mark A., Kitange, Gaspar J., Decker, Paul A., Giannini, Caterina, Wu, Wenting, Ballman, Karla A., James, C. David, Sarkaria, Jann N.
Publicado em 2009

Evaluation of MGMT Promoter Methylation Status and Correlation with Temozolomide Response in Orthotopic Glioblastoma Xenograft Model

Por Kitange, Gaspar J., Carlson, Brett L., Mladek, Ann C., Decker, Paul A., Schroeder, Mark A., Wu, Wenting, Grogan, Patrick T., Giannini, Caterina, Ballman, Karla V., Buckner, Jan C., James, C. David, Sarkaria, Jann N.
Publicado em 2008

Characterization and Gene Expression Profiling in Glioma Cell Lines with Deletion of Chromosome 19 Before and After Microcell-Mediated Restoration of Normal Human Chromosome 19

Por Drucker, Kristen L., Kitange, Gaspar J., Kollmeyer, Thomas M., Law, Mark E., Passe, Sandra, Rynearson, Amanda L., Blair, Hilary, Soderberg, Cheryl L., Morlan, Bruce W., Ballman, Karla V., Giannini, Caterina, Jenkins, Robert B.
Publicado em 2009

Retinoblastoma Binding Protein 4 Modulates Temozolomide Sensitivity in Glioblastoma by Regulating DNA Repair Proteins

Por Kitange, Gaspar J., Mladek, Ann C., Schroeder, Mark A., Pokorny, Jenny C., Carlson, Brett L., Zhang, Yuji, Nair, Asha A., Lee, Jeong-Heon, Yan, Huihuang, Decker, Paul A., Zhang, Zhiguo, Sarkaria, Jann N.
Publicado no Cell Rep (2016)

Efficacy of protracted temozolomide dosing is limited in MGMT unmethylated GBM xenograft models

Por Cen, Ling, Carlson, Brett L., Pokorny, Jenny L., Mladek, Ann C., Grogan, Patrick T., Schroeder, Mark A., Decker, Paul A., Anderson, S. Keith, Giannini, Caterina, Wu, Wenting, Ballman, Karla V., Kitange, Gaspar J., Sarkaria, Jann N.
Publicado em 2013

Inhibition of Histone Deacetylation Potentiates the Evolution of Acquired Temozolomide Resistance Linked to MGMT Upregulation in Glioblastoma Xenografts()

Por Kitange, Gaspar J., Mladek, Ann C., Carlson, Brett L., Schroeder, Mark A., Pokorny, Jenny L., Cen, Ling, Decker, Paul A., Wu, Wenting, Lomberk, Gwen A., Gupta, Shiv K., Urrutia, Raul A., Sarkaria, Jann N.
Publicado em 2012

The role of LAT1 in (18)F-DOPA uptake in malignant gliomas

Por Youland, Ryan S., Kitange, Gaspar J., Peterson, Timothy E., Pafundi, Deanna H., Ramiscal, Judi A., Pokorny, Jenny L., Giannini, Caterina, Laack, Nadia N., Parney, Ian F., Lowe, Val J., Brinkmann, Debra H., Sarkaria, Jann N.
Publicado em 2012

p16-Cdk4-Rb axis controls sensitivity to a cyclin-dependent kinase inhibitor PD0332991 in glioblastoma xenograft cells

Por Cen, Ling, Carlson, Brett L., Schroeder, Mark A., Ostrem, Jamie L., Kitange, Gaspar J., Mladek, Ann C., Fink, Stephanie R., Decker, Paul A., Wu, Wenting, Kim, Jung-Sik, Waldman, Todd, Jenkins, Robert B., Sarkaria, Jann N.
Publicado em 2012

PTEN Loss Does Not Predict for Response to RAD001 (Everolimus) in a Glioblastoma Orthotopic Xenograft Test Panel

Por Yang, Lin, Clarke, Michelle J., Carlson, Brett L., Mladek, Ann C., Schroeder, Mark A., Decker, Paul, Wu, Wenting, Kitange, Gaspar J., Grogan, Patrick T., Goble, Jennie M., Uhm, Joon, Galanis, Evanthia, Giannini, Caterina, Lane, Heidi A., James, C. David, Sarkaria, Jann N.
Publicado em 2008

Restricted delivery of talazoparib across the blood-brain barrier limits the sensitizing effects of poly (ADP-ribose) polymerase inhibition on temozolomide therapy in glioblastoma

Por Kizilbash, Sani H., Gupta, Shiv K., Chang, Kenneth, Kawashima, Ryo, Parrish, Karen E., Carlson, Brett L., Bakken, Katrina K., Mladek, Ann C., Schroeder, Mark A., Decker, Paul A., Kitange, Gaspar J., Shen, Yuqiao, Feng, Ying, Protter, Andrew A., Elmquist, William F., Sarkaria, Jann N.
Publicado no Mol Cancer Ther (2017)

Delineation of MGMT Hypermethylation as a Biomarker for Veliparib-Mediated Temozolomide-Sensitizing Therapy of Glioblastoma

Por Gupta, Shiv K., Kizilbash, Sani H., Carlson, Brett L., Mladek, Ann C., Boakye-Agyeman, Felix, Bakken, Katrina K., Pokorny, Jenny L., Schroeder, Mark A., Decker, Paul A., Cen, Ling, Eckel-Passow, Jeanette E., Sarkar, Gobinda, Ballman, Karla V., Reid, Joel M., Jenkins, Robert B., Verhaak, Roeland G., Sulman, Erik P., Kitange, Gaspar J., Sarkaria, Jann N.
Publicado no J Natl Cancer Inst (2015)