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Expression of CD74 in high Grade Gliomas: A Potential Role in Temozolomide Resistance
Temozolomide (TMZ) is the most effective chemotherapeutic agent for glioblastoma (GBM). Resistance to this methylating agent is linked to DNA repair enzyme O6-methylguanine-DNA methyltransferase (MGMT). However, in recent studies MGMT status was not completely accurate as a predictor of TMZ response...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3233976/ https://ncbi.nlm.nih.gov/pubmed/20443131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-010-0186-9 |
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