Radiosensitizing effects of TMZ observed in vivo only in a subset of MGMT methylated GBM xenografts

PURPOSE: Concurrent temozolomide (TMZ) and radiation therapy (RT) followed by adjuvant TMZ is standard treatment for patients with GBM, although the relative contribution of concurrent versus adjuvant TMZ is unknown. In this study, the efficacy of TMZ/RT was tested in a panel of 20 primary GBM xenog...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Carlson, Brett L., Grogan, Patrick T., Mladek, Ann C., Schroeder, Mark A., Kitange, Gaspar J., Decker, Paul A., Giannini, Caterina, Wu, Wenting, Ballman, Karla A., James, C. David, Sarkaria, Jann N.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773462/
https://ncbi.nlm.nih.gov/pubmed/19695438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2009.04.026
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki