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Efficacy of protracted temozolomide dosing is limited in MGMT unmethylated GBM xenograft models
BACKGROUND: Temozolomide (TMZ) is important chemotherapy for glioblastoma multiforme (GBM), but the optimal dosing schedule is unclear. METHODS: The efficacies of different clinically relevant dosing regimens were compared in a panel of 7 primary GBM xenografts in an intracranial therapy evaluation...
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| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3661094/ https://ncbi.nlm.nih.gov/pubmed/23479134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not010 |
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