Efficacy of protracted temozolomide dosing is limited in MGMT unmethylated GBM xenograft models

BACKGROUND: Temozolomide (TMZ) is important chemotherapy for glioblastoma multiforme (GBM), but the optimal dosing schedule is unclear. METHODS: The efficacies of different clinically relevant dosing regimens were compared in a panel of 7 primary GBM xenografts in an intracranial therapy evaluation...

詳細記述

保存先:
書誌詳細
主要な著者: Cen, Ling, Carlson, Brett L., Pokorny, Jenny L., Mladek, Ann C., Grogan, Patrick T., Schroeder, Mark A., Decker, Paul A., Anderson, S. Keith, Giannini, Caterina, Wu, Wenting, Ballman, Karla V., Kitange, Gaspar J., Sarkaria, Jann N.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2013
主題:
Basic and Translational Investigations
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661094/
https://ncbi.nlm.nih.gov/pubmed/23479134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not010
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