Quantitative phosphoproteomics reveals Wee1 kinase as a therapeutic target in a model of proneural glioblastoma

by Lescarbeau, Rebecca S., Lei, Liang, Bakken, Katrina K., Sims, Peter A., Sarkaria, Jann N., Canoll, Peter, White, Forest M.
Published in Mol Cancer Ther (2016)

EXTH-12. INHIBITION OF CBP/p300 HISTONE ACETYLATION ACTIVITY ENHANCES TEMOZOLOMIDE ACTIVITY IN GLIOBLASTOMA PATIENT DERIVED XENOGRAFTS

by Kitange, Gaspar J, Burgenske, Danielle M, Bakken, Katrina K, Hu, Zeng, He, Lihong, Carlson, Brett L, Wilson, Jonathan, Bommi-Reddy, Archana, Conery, Andy, Sarkaria, Jann
Published in Neuro Oncol (2020)

Heterogeneous Binding and Central Nervous System Distribution of the Multitargeted Kinase Inhibitor Ponatinib Restrict Orthotopic Efficacy in a Patient-Derived Xenograft Model of G...

by Laramy, Janice K., Kim, Minjee, Gupta, Shiv K., Parrish, Karen E., Zhang, Shuangling, Bakken, Katrina K., Carlson, Brett L., Mladek, Ann C., Ma, Daniel J., Sarkaria, Jann N., Elmquist, William F.
Published in J Pharmacol Exp Ther (2017)

Quantitative Analysis of Tyrosine Phosphorylation from FFPE Tissues Reveals Patient-Specific Signaling Networks

by Kohale, Ishwar N., Burgenske, Danielle M., Mladek, Ann C., Bakken, Katrina K., Kuang, Jenevieve, Boughey, Judy C., Wang, Liewei, Carter, Jodi M., Haura, Eric B., Goetz, Matthew P., Sarkaria, Jann N., White, Forest M.
Published in Cancer Res (2021)

In vivo efficacy of tesevatinib in patient-derived xenograft glioblastoma models may be limited by tissue binding and compensatory signaling

by Kizilbash, Sani H., Gupta, Shiv K., Parrish, Karen E., Laramy, Janice K., Kim, Minjee, Gampa, Gautham, Carlson, Brett L., Bakken, Katrina K., Mladek, Ann C., Schroeder, Mark A., Decker, Paul A., Elmquist, William F, Sarkaria, Jann N.
Published in Mol Cancer Ther (2021)

Restricted delivery of talazoparib across the blood-brain barrier limits the sensitizing effects of poly (ADP-ribose) polymerase inhibition on temozolomide therapy in glioblastoma

by Kizilbash, Sani H., Gupta, Shiv K., Chang, Kenneth, Kawashima, Ryo, Parrish, Karen E., Carlson, Brett L., Bakken, Katrina K., Mladek, Ann C., Schroeder, Mark A., Decker, Paul A., Kitange, Gaspar J., Shen, Yuqiao, Feng, Ying, Protter, Andrew A., Elmquist, William F., Sarkaria, Jann N.
Published in Mol Cancer Ther (2017)

The efficacy of the Wee1 inhibitor MK-1775 combined with temozolomide is limited by heterogeneous distribution across the blood-brain barrier in glioblastoma

by Pokorny, Jenny L., Calligaris, David, Gupta, Shiv K., Iyekegbe, Dennis O., Mueller, Dustin, Bakken, Katrina K., Carlson, Brett L., Schroeder, Mark A., Evans, Debra L., Lou, Zhenkun, Decker, Paul A., Eckel-Passow, Jeanette E., Pucci, Vincenzo, Ma, Bennett, Shumway, Stuart D., Elmquist, William, Agar, Nathalie Y., Sarkaria, Jann N.
Published in Clin Cancer Res (2015)

EXTH-01. INHIBITION OF DNA-PKcs BY M3814 POTENTIATES EFFICACY OF IONIZING RADIATION IN PATIENT-DERIVED XENOGRAFTS OF MELANOMA BRAIN METASTASES

by Ji, Jianxiong, Smith, Emily, Sarkaria, Paige, Mladek, Ann, Talele, Surabhi, Swanson, Katelyn, Mohammad, Afroz S, Zhang, Wenjuan, He, Lihong, Hu, Zeng, Zhao, Yu, Chen, Jiajia, Connors, Margaret A, Porath, Kendra A, Bakken, Katrina K, Dragojevic, Sonja, Carlson, Brett L, Gupta, Shiv K, Burgenske, Danielle M, Kitange, Gaspar J, Elmquist, William F, Sarkaria, Jann
Published in Neuro Oncol (2020)

Delineation of MGMT Hypermethylation as a Biomarker for Veliparib-Mediated Temozolomide-Sensitizing Therapy of Glioblastoma

by Gupta, Shiv K., Kizilbash, Sani H., Carlson, Brett L., Mladek, Ann C., Boakye-Agyeman, Felix, Bakken, Katrina K., Pokorny, Jenny L., Schroeder, Mark A., Decker, Paul A., Cen, Ling, Eckel-Passow, Jeanette E., Sarkar, Gobinda, Ballman, Karla V., Reid, Joel M., Jenkins, Robert B., Verhaak, Roeland G., Sulman, Erik P., Kitange, Gaspar J., Sarkaria, Jann N.
Published in J Natl Cancer Inst (2015)