Pharmacokinetic Assessment of Cooperative Efflux of the Multitargeted Kinase Inhibitor Ponatinib Across the Blood-Brain Barrier

Por Laramy, Janice K., Kim, Minjee, Parrish, Karen E., Sarkaria, Jann N., Elmquist, William F.
Publicado no J Pharmacol Exp Ther (2018)

Brain Distribution of a Novel MEK Inhibitor E6201: Implications in the Treatment of Melanoma Brain Metastases

Por Gampa, Gautham, Kim, Minjee, Cook-Rostie, Nicholas, Laramy, Janice K., Sarkaria, Jann N., Paradiso, Linda, DePalatis, Louis, Elmquist, William F.
Publicado no Drug Metab Dispos (2018)

Heterogeneous Binding and Central Nervous System Distribution of the Multitargeted Kinase Inhibitor Ponatinib Restrict Orthotopic Efficacy in a Patient-Derived Xenograft Model of G...

Por Laramy, Janice K., Kim, Minjee, Gupta, Shiv K., Parrish, Karen E., Zhang, Shuangling, Bakken, Katrina K., Carlson, Brett L., Mladek, Ann C., Ma, Daniel J., Sarkaria, Jann N., Elmquist, William F.
Publicado no J Pharmacol Exp Ther (2017)

Is the blood–brain barrier really disrupted in all glioblastomas? A critical assessment of existing clinical data

Por Sarkaria, Jann N, Hu, Leland S, Parney, Ian F, Pafundi, Deanna H, Brinkmann, Debra H, Laack, Nadia N, Giannini, Caterina, Burns, Terence C, Kizilbash, Sani H, Laramy, Janice K, Swanson, Kristin R, Kaufmann, Timothy J, Brown, Paul D, Agar, Nathalie Y R, Galanis, Evanthia, Buckner, Jan C, Elmquist, William F
Publicado no Neuro Oncol (2018)