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Quantitative phosphoproteomics reveals Wee1 kinase as a therapeutic target in a model of proneural glioblastoma

Glioblastoma (GBM) is the most common malignant primary brain cancer. With a median survival of about a year, new approaches to treating this disease are necessary. To identify signaling molecules regulating GBM progression in a genetically engineered murine model of proneural GBM, we quantified pho...

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Bibliografske podrobnosti
izdano v:Mol Cancer Ther
Main Authors: Lescarbeau, Rebecca S., Lei, Liang, Bakken, Katrina K., Sims, Peter A., Sarkaria, Jann N., Canoll, Peter, White, Forest M.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893926/
https://ncbi.nlm.nih.gov/pubmed/27196784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0692-T
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