Quantitative, Multiplexed Assays for Low Abundance Proteins in Plasma by Targeted Mass Spectrometry and Stable Isotope Dilution

Por Keshishian, Hasmik, Addona, Terri, Burgess, Michael, Kuhn, Eric, Carr, Steven A.
Publicado em 2007

Automated Detection of Inaccurate and Imprecise Transitions in Peptide Quantification by Multiple Reaction Monitoring Mass Spectrometry

Por Abbatiello, Susan E., Mani, D. R., Keshishian, Hasmik, Carr, Steven A.
Publicado em 2009

Simplified and Efficient Quantification of Low-abundance Proteins at Very High Multiplex via Targeted Mass Spectrometry

Por Burgess, Michael W., Keshishian, Hasmik, Mani, D. R., Gillette, Michael A., Carr, Steven A.
Publicado em 2014

Accurate Inclusion Mass Screening: A Bridge from Unbiased Discovery to Targeted Assay Development for Biomarker Verification

Por Jaffe, Jacob D., Keshishian, Hasmik, Chang, Betty, Addona, Theresa A., Gillette, Michael A., Carr, Steven A.
Publicado em 2008

Quantitative, multiplexed workflow for deep analysis of human blood plasma and biomarker discovery by mass spectrometry

Por Keshishian, Hasmik, Burgess, Michael W, Specht, Harrison, Wallace, Luke, Clauser, Karl R, Gillette, Michael A, Carr, Steven A
Publicado no Nat Protoc (2017)

Quantification of Cardiovascular Biomarkers in Patient Plasma by Targeted Mass Spectrometry and Stable Isotope Dilution

Por Keshishian, Hasmik, Addona, Terri, Burgess, Michael, Mani, D. R., Shi, Xu, Kuhn, Eric, Sabatine, Marc S., Gerszten, Robert E., Carr, Steven A.
Publicado em 2009

Developing Multiplexed Assays for Troponin I and Interleukin-33 in Plasma by Peptide Immunoaffinity Enrichment and Targeted Mass Spectrometry

Por Kuhn, Eric, Addona, Terri, Keshishian, Hasmik, Burgess, Michael, Mani, D.R., Lee, Richard T., Sabatine, Marc S., Gerszten, Robert E., Carr, Steven A.
Publicado em 2009

Multiplexed, Quantitative Workflow for Sensitive Biomarker Discovery in Plasma Yields Novel Candidates for Early Myocardial Injury

Por Keshishian, Hasmik, Burgess, Michael W., Gillette, Michael A., Mertins, Philipp, Clauser, Karl R., Mani, D. R., Kuhn, Eric W., Farrell, Laurie A., Gerszten, Robert E., Carr, Steven A.
Publicado no Mol Cell Proteomics (2015)

Rictor Phosphorylation on the THR-1135 Site Does Not Require Mammalian Target of Rapamycin Complex 2

Por Boulbes, Delphine, Chen, Chien-Hung, Shaikenov, Tattym, Agarwal, Nitin K., Peterson, Timothy R., Addona, Terri A., Keshishian, Hasmik, Carr, Steven A., Magnuson, Mark A., Sabatini, David M., Sarbassov, Dos D.
Publicado em 2010

A pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease

Por Addona, Terri A, Shi, Xu, Keshishian, Hasmik, Mani, D R, Burgess, Michael, Gillette, Michael A, Clauser, Karl R, Shen, Dongxiao, Lewis, Gregory D, Farrell, Laurie A, Fifer, Michael A, Sabatine, Marc S, Gerszten, Robert E, Carr, Steven A
Publicado em 2011

A Curated Resource for Phosphosite-specific Signature Analysis

Por Krug, Karsten, Mertins, Philipp, Zhang, Bin, Hornbeck, Peter, Raju, Rajesh, Ahmad, Rushdy, Szucs, Matthew, Mundt, Filip, Forestier, Dominique, Jane-Valbuena, Judit, Keshishian, Hasmik, Gillette, Michael A., Tamayo, Pablo, Mesirov, Jill P., Jaffe, Jacob D., Carr, Steven A., Mani, D. R.
Publicado no Mol Cell Proteomics (2019)

Aptamer-Based Proteomic Profiling Reveals Novel Candidate Biomarkers and Pathways in Cardiovascular Disease

Por Ngo, Debby, Sinha, Sumita, Shen, Dongxiao, Kuhn, Eric W., Keyes, Michelle J., Shi, Xu, Benson, Mark D., O’ Sullivan, John F., Keshishian, Hasmik, Farrell, Laurie A., Fifer, Michael A., Vasan, Ramachandran S., Sabatine, Marc S., Larson, Martin G., Carr, Steven A., Wang, Thomas J., Gerszten, Robert E.
Publicado no Circulation (2016)

New Guidelines for Publication of Manuscripts Describing Development and Application of Targeted Mass Spectrometry Measurements of Peptides and Proteins

Por Abbatiello, Susan, Ackermann, Bradley L., Borchers, Christoph, Bradshaw, Ralph A., Carr, Steven A., Chalkley, Robert, Choi, Meena, Deutsch, Eric, Domon, Bruno, Hoofnagle, Andrew N., Keshishian, Hasmik, Kuhn, Eric, Liebler, Daniel C., MacCoss, Michael, MacLean, Brendan, Mani, DR, Neubert, Hendrik, Smith, Derek, Vitek, Olga, Zimmerman, Lisa
Publicado no Mol Cell Proteomics (2017)

Patterns of substrate affinity, competition, and degradation kinetics underlie biological activity of thalidomide analogs

Por Sperling, Adam S., Burgess, Michael, Keshishian, Hasmik, Gasser, Jessica A., Bhatt, Shruti, Jan, Max, Słabicki, Mikołaj, Sellar, Rob S., Fink, Emma C., Miller, Peter G., Liddicoat, Brian J., Sievers, Quinlan L., Sharma, Rohan, Adams, Dylan N., Olesinski, Elyse A., Fulciniti, Mariateresa, Udeshi, Namrata D., Kuhn, Eric, Letai, Anthony, Munshi, Nikhil C., Carr, Steven A., Ebert, Benjamin L.
Publicado no Blood (2019)

Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injury

Por Lewis, Gregory D., Wei, Ru, Liu, Emerson, Yang, Elaine, Shi, Xu, Martinovic, Maryann, Farrell, Laurie, Asnani, Aarti, Cyrille, Marcoli, Ramanathan, Arvind, Shaham, Oded, Berriz, Gabriel, Lowry, Patricia A., Palacios, Igor F., Taşan, Murat, Roth, Frederick P., Min, Jiangyong, Baumgartner, Christian, Keshishian, Hasmik, Addona, Terri, Mootha, Vamsi K., Rosenzweig, Anthony, Carr, Steven A., Fifer, Michael A., Sabatine, Marc S., Gerszten, Robert E.
Publicado em 2008

A large peptidome dataset improves HLA class I epitope prediction across most of the human population

Por Sarkizova, Siranush, Klaeger, Susan, Le, Phuong M., Li, Letitia W., Oliveira, Giacomo, Keshishian, Hasmik, Hartigan, Christina R., Zhang, Wandi, Braun, David A., Ligon, Keith L., Bachireddy, Pavan, Zervantonakis, Ioannis K., Rosenbluth, Jennifer M., Ouspenskaia, Tamara, Law, Travis, Justesen, Sune, Stevens, Jonathan, Lane, William J., Eisenhaure, Thomas, Zhang, Guang Lan, Clauser, Karl R., Hacohen, Nir, Carr, Steven A., Wu, Catherine J., Keskin, Derin B.
Publicado no Nat Biotechnol (2019)

Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis

Por Khajuria, Rajiv K., Munschauer, Mathias, Ulirsch, Jacob C., Fiorini, Claudia, Ludwig, Leif S., McFarland, Sean K., Abdulhay, Nour J., Specht, Harrison, Keshishian, Hasmik, Mani, D.R., Jovanovic, Marko, Ellis, Steven R., Fulco, Charles P., Engreitz, Jesse M., Schütz, Sabina, Lian, John, Gripp, Karen W., Weinberg, Olga K., Pinkus, Geraldine S., Gehrke, Lee, Regev, Aviv, Lander, Eric S., Gazda, Hanna T., Lee, Winston Y., Panse, Vikram G., Carr, Steven A., Sankaran, Vijay G.
Publicado no Cell (2018)

BRG1 loss predisposes lung cancers to replicative stress and ATR dependency

Por Gupta, Manav, Concepcion, Carla P., Fahey, Caroline G., Keshishian, Hasmik, Bhutkar, Arjun, Brainson, Christine F., Sanchez-Rivera, Francisco J., Pessina, Patrizia, Kim, Jonathan Y., Simoneau, Antoine, Paschini, Margherita, Beytagh, Mary C., Stanclift, Caroline R., Schenone, Monica, Mani, D R., Li, Chendi, Oh, Audris, Li, Fei, Hu, Hai, Karatza, Angeliki, Bronson, Roderick T., Shaw, Alice T., Hata, Aaron N., Wong, Kwok-Kin, Zou, Lee, Carr, Steven A., Jacks, Tyler, Kim, Carla F.
Publicado no Cancer Res (2020)

Reproducible workflow for multiplexed deep-scale proteome and phosphoproteome analysis of tumor tissues by liquid chromatography-mass spectrometry

Por Mertins, Philipp, Tang, Lauren C., Krug, Karsten, Clark, David J., Gritsenko, Marina A., Chen, Lijun, Clauser, Karl R., Clauss, Therese R., Shah, Punit, Gillette, Michael A., Petyuk, Vladislav A., Thomas, Stefani N., Mani, D. R., Mundt, Filip, Moore, Ronald J., Hu, Yingwei, Zhao, Rui, Schnaubelt, Michael, Keshishian, Hasmik, Monroe, Matthew E., Zhang, Zhen, Udeshi, Namrata D., Mani, Deepak, Davies, Sherri R., Townsend, R. Reid, Chan, Daniel W., Smith, Richard D., Zhang, Hui, Liu, Tao, Carr, Steven A.
Publicado no Nat Protoc (2018)

Large-Scale Interlaboratory Study to Develop, Analytically Validate and Apply Highly Multiplexed, Quantitative Peptide Assays to Measure Cancer-Relevant Proteins in Plasma

Por Abbatiello, Susan E., Schilling, Birgit, Mani, D. R., Zimmerman, Lisa J., Hall, Steven C., MacLean, Brendan, Albertolle, Matthew, Allen, Simon, Burgess, Michael, Cusack, Michael P., Gosh, Mousumi, Hedrick, Victoria, Held, Jason M., Inerowicz, H. Dorota, Jackson, Angela, Keshishian, Hasmik, Kinsinger, Christopher R., Lyssand, John, Makowski, Lee, Mesri, Mehdi, Rodriguez, Henry, Rudnick, Paul, Sadowski, Pawel, Sedransk, Nell, Shaddox, Kent, Skates, Stephen J., Kuhn, Eric, Smith, Derek, Whiteaker, Jeffery R., Whitwell, Corbin, Zhang, Shucha, Borchers, Christoph H., Fisher, Susan J., Gibson, Bradford W., Liebler, Daniel C., MacCoss, Michael J., Neubert, Thomas A., Paulovich, Amanda G., Regnier, Fred E., Tempst, Paul, Carr, Steven A.
Publicado no Mol Cell Proteomics (2015)