Moonshots for aging

le Kumar, Sandeep, Peterson, Timothy R.
Foilsithe in Nutr Healthy Aging (2020)

Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress

le Sengupta, Shomit, Peterson, Timothy R., Sabatini, David M.
Foilsithe 2010

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

le Sancak, Yasemin, Peterson, Timothy R., Shaul, Yoav D., Lindquist, Robert A., Thoreen, Carson C., Bar-Peled, Liron, Sabatini, David M.
Foilsithe 2008

Paradoxical expression of INK4c in proliferative multiple myeloma tumors: bi-allelic deletion vs increased expression

le Dib, Amel, Peterson, Timothy R, Raducha-Grace, Laura, Zingone, Adriana, Zhan, Fenghuang, Hanamura, Ichiro, Barlogie, Bart, Shaughnessy, John, Kuehl, W Michael
Foilsithe 2006

DEPTOR is an mTOR Inhibitor Whose Frequent Overexpression in Multiple Myeloma Cells Promotes their Survival

le Peterson, Timothy R., Laplante, Mathieu, Thoreen, Carson C., Sancak, Yasemin, Kang, Seong A., Kuehl, W. Michael, Gray, Nathanael S., Sabatini, David M.
Foilsithe 2009

Postprandial Hepatic Lipid Metabolism Requires Signaling though Akt2 Independent of the Transcription Factors FoxA2, FoxO1 and SREBP1c

le Wan, Min, Leavens, Karla F., Saleh, Danish, Easton, Rachael M., Guertin, David A., Peterson, Timothy R., Kaestner, Klaus H., Sabatini, David M., Birnbaum, Morris J.
Foilsithe 2011

Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates

le Yu, Zhou, Surface, Lauren E, Park, Chong Yon, Horlbeck, Max A, Wyant, Gregory A, Abu-Remaileh, Monther, Peterson, Timothy R, Sabatini, David M, Weissman, Jonathan S, O'Shea, Erin K
Foilsithe in eLife (2018)

Rictor Phosphorylation on the THR-1135 Site Does Not Require Mammalian Target of Rapamycin Complex 2

le Boulbes, Delphine, Chen, Chien-Hung, Shaikenov, Tattym, Agarwal, Nitin K., Peterson, Timothy R., Addona, Terri A., Keshishian, Hasmik, Carr, Steven A., Magnuson, Mark A., Sabatini, David M., Sarbassov, Dos D.
Foilsithe 2010

The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling

le Hsu, Peggy P., Kang, Seong A., Rameseder, Jonathan, Zhang, Yi, Ottina, Kathleen A., Lim, Daniel, Peterson, Timothy R., Choi, Yongmun, Gray, Nathanael S., Yaffe, Michael B., Marto, Jarrod A., Sabatini, David M.
Foilsithe 2011

mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway

le Peterson, Timothy R., Sengupta, Shomit S., Harris, Thurl E., Carmack, Anne E., Kang, Seong A., Balderas, Eric, Guertin, David A., Madden, Katherine L., Carpenter, Anne E., Finck, Brian N., Sabatini, David M.
Foilsithe 2011

ATRAID regulates the action of nitrogen-containing bisphosphonates on bone

le Surface, Lauren E., Burrow, Damon T., Li, Jinmei, Park, Jiwoong, Kumar, Sandeep, Lyu, Cheng, Song, Niki, Yu, Zhou, Rajagopal, Abbhirami, Bae, Yangjin, Lee, Brendan H., Mumm, Steven, Gu, Charles C., Baker, Jonathan C., Mohseni, Mahshid, Sum, Melissa, Huskey, Margaret, Duan, Shenghui, Bijanki, Vinieth N., Civitelli, Roberto, Gardner, Michael J., McAndrew, Chris M., Ricci, William M., Gurnett, Christina A., Diemer, Kathryn, Wan, Fei, Costantino, Christina L., Shannon, Kristen M., Raje, Noopur, Dodson, Thomas B., Haber, Daniel A., Carette, Jan E., Varadarajan, Malini, Brummelkamp, Thijn R., Birsoy, Kivanc, Sabatini, David M., Haller, Gabe, Peterson, Timothy R.
Foilsithe in Sci Transl Med (2020)