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Paradoxical expression of INK4c in proliferative multiple myeloma tumors: bi-allelic deletion vs increased expression

BACKGROUND: A high proliferative capacity of tumor cells usually is associated with shortened patient survival. Disruption of the RB pathway, which is critically involved in regulating the G1 to S cell cycle transition, is a frequent target of oncogenic events that are thought to contribute to incre...

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Autors principals: Dib, Amel, Peterson, Timothy R, Raducha-Grace, Laura, Zingone, Adriana, Zhan, Fenghuang, Hanamura, Ichiro, Barlogie, Bart, Shaughnessy, John, Kuehl, W Michael
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1634742/
https://ncbi.nlm.nih.gov/pubmed/17049078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-1-23
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