Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma

Two oncogenic pathways have been hypothesized for multiple myeloma (MM) and premalignant monoclonal gammopathy of undetermined significance (MGUS) tumors: a nonhyperdiploid pathway associated with a high prevalence of IgH translocations and a hyperdiploid pathway associated with multiple trisomies o...

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Detalhes bibliográficos
Main Authors: Bergsagel, P. Leif, Kuehl, W. Michael, Zhan, Fenghuang, Sawyer, Jeffrey, Barlogie, Bart, Shaughnessy, John
Formato: Artigo
Idioma:Inglês
Publicado em: © 2005 by The American Society of Hematology 2005
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895118/
https://ncbi.nlm.nih.gov/pubmed/15755896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-01-0034
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