The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling

The mTOR protein kinase is a master growth promoter that nucleates two complexes, mTORC1 and mTORC2. Despite the diverse processes controlled by mTOR, few substrates are known. We defined the mTOR-regulated phosphoproteome by quantitative mass spectrometry and characterized the primary sequence moti...

詳細記述

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書誌詳細
主要な著者: Hsu, Peggy P., Kang, Seong A., Rameseder, Jonathan, Zhang, Yi, Ottina, Kathleen A., Lim, Daniel, Peterson, Timothy R., Choi, Yongmun, Gray, Nathanael S., Yaffe, Michael B., Marto, Jarrod A., Sabatini, David M.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177140/
https://ncbi.nlm.nih.gov/pubmed/21659604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1199498
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