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Phospholipase D–dependent mTOR complex 1 (mTORC1) activation by glutamine

Glutamine is a key nutrient required for sustaining cell proliferation, contributing to nucleotide, protein, and lipid synthesis. The mTOR complex 1 (mTORC1) is a highly conserved protein complex that acts as a sensor of nutrients, relaying signals for the shift from catabolic to anabolic metabolism...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Bernfeld, Elyssa, Menon, Deepak, Vaghela, Vishaldeep, Zerin, Ismat, Faruque, Promie, Frias, Maria A., Foster, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200938/
https://ncbi.nlm.nih.gov/pubmed/30194281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004972
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