mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway

The nutrient- and growth factor-responsive kinase, mTOR Complex 1 (mTORC1) regulates many processes that control growth including protein synthesis, autophagy, and lipogenesis. Through unknown mechanisms, mTORC1 promotes the function of SREBP, a master regulator of lipo- and sterolgenic gene transcr...

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Detalhes bibliográficos
Main Authors: Peterson, Timothy R., Sengupta, Shomit S., Harris, Thurl E., Carmack, Anne E., Kang, Seong A., Balderas, Eric, Guertin, David A., Madden, Katherine L., Carpenter, Anne E., Finck, Brian N., Sabatini, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336367/
https://ncbi.nlm.nih.gov/pubmed/21816276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.06.034
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