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Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress

The large serine/threonine protein kinase mTOR regulates cellular and organismal homeostasis by coordinating anabolic and catabolic processes with nutrient, energy, and oxygen availability and growth factor signaling. Cells and organisms experience a wide variety of insults that perturb the homeosta...

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Detalhes bibliográficos
Main Authors: Sengupta, Shomit, Peterson, Timothy R., Sabatini, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993060/
https://ncbi.nlm.nih.gov/pubmed/20965424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.09.026
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