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The TSC-mTOR pathway regulates macrophage polarization

Macrophages are able to polarize to proinflammatory M1 or alternative M2 states with distinct phenotypes and physiological functions. How metabolic status regulates macrophage polarization remains not well understood, and here we examine the role of mTOR (Mechanistic Target of Rapamycin), a central...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Byles, Vanessa, Covarrubias, Anthony J., Ben-Sahra, Issam, Lamming, Dudley W., Sabatini, David M., Manning, Brendan D., Horng, Tiffany
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876736/
https://ncbi.nlm.nih.gov/pubmed/24280772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3834
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