The TSC-mTOR pathway regulates macrophage polarization

Macrophages are able to polarize to proinflammatory M1 or alternative M2 states with distinct phenotypes and physiological functions. How metabolic status regulates macrophage polarization remains not well understood, and here we examine the role of mTOR (Mechanistic Target of Rapamycin), a central...

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Bibliografische gegevens
Hoofdauteurs: Byles, Vanessa, Covarrubias, Anthony J., Ben-Sahra, Issam, Lamming, Dudley W., Sabatini, David M., Manning, Brendan D., Horng, Tiffany
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876736/
https://ncbi.nlm.nih.gov/pubmed/24280772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3834
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