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Twenty-five years of mTOR: Uncovering the link from nutrients to growth

In my PNAS Inaugural Article, I describe the development of the mTOR field, starting with efforts to understand the mechanism of action of the drug rapamycin, which ∼25 y ago led to the discovery of the mTOR protein kinase. I focus on insights that we have contributed and on work that has been parti...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Autor principal: Sabatini, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692607/
https://ncbi.nlm.nih.gov/pubmed/29078414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716173114
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