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mTOR at the nexus of nutrition, growth, ageing and disease

The mTOR pathway integrates a diverse set of environmental cues, such as growth factor signals and nutritional status, to direct eukaryotic cell growth. Over the past two and a half decades, mapping of the mTOR signalling landscape has revealed that mTOR controls biomass accumulation and metabolism...

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Detalhes bibliográficos
Publicado no:Nat Rev Mol Cell Biol
Main Authors: Liu, Grace Y., Sabatini, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7102936/
https://ncbi.nlm.nih.gov/pubmed/31937935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41580-019-0199-y
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