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Rapalogs and mTOR inhibitors as anti-aging therapeutics
Rapamycin, an inhibitor of mechanistic target of rapamycin (mTOR), has the strongest experimental support to date as a potential anti-aging therapeutic in mammals. Unlike many other compounds that have been claimed to influence longevity, rapamycin has been repeatedly tested in long-lived, genetical...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3582126/ https://ncbi.nlm.nih.gov/pubmed/23454761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64099 |
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