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New perspectives on mTOR inhibitors (rapamycin, rapalogs and TORKinibs) in transplantation

The macrolide rapamycin and its analogues (rapalogs) constitute the first generation of mammalian target of rapamycin (mTOR) inhibitors. Since the introduction of rapamycin as an immunosuppressant, there has been extensive progress in understanding its complex mechanisms of action. New insights into...

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Publicat a:Br J Clin Pharmacol
Autors principals: Waldner, Matthias, Fantus, Daniel, Solari, Mario, Thomson, Angus W.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061789/
https://ncbi.nlm.nih.gov/pubmed/26810941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12893
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