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New perspectives on mTOR inhibitors (rapamycin, rapalogs and TORKinibs) in transplantation

The macrolide rapamycin and its analogues (rapalogs) constitute the first generation of mammalian target of rapamycin (mTOR) inhibitors. Since the introduction of rapamycin as an immunosuppressant, there has been extensive progress in understanding its complex mechanisms of action. New insights into...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Waldner, Matthias, Fantus, Daniel, Solari, Mario, Thomson, Angus W.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061789/
https://ncbi.nlm.nih.gov/pubmed/26810941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12893
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