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New perspectives on mTOR inhibitors (rapamycin, rapalogs and TORKinibs) in transplantation

The macrolide rapamycin and its analogues (rapalogs) constitute the first generation of mammalian target of rapamycin (mTOR) inhibitors. Since the introduction of rapamycin as an immunosuppressant, there has been extensive progress in understanding its complex mechanisms of action. New insights into...

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Bibliografiske detaljer
Udgivet i:Br J Clin Pharmacol
Main Authors: Waldner, Matthias, Fantus, Daniel, Solari, Mario, Thomson, Angus W.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061789/
https://ncbi.nlm.nih.gov/pubmed/26810941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12893
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