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Roles of mTOR complexes in the kidney: implications for renal disease and transplantation

The mTOR pathway has a central role in the regulation of cell metabolism, growth and proliferation. Studies involving selective gene targeting of mTOR complexes (mTORC1 and mTORC2) in renal cell populations and/or pharmacologic mTOR inhibition have revealed important roles of mTOR in podocyte homeos...

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Bibliografske podrobnosti
izdano v:Nat Rev Nephrol
Main Authors: Fantus, Daniel, Rogers, Natasha M., Grahammer, Florian, Huber, Tobias B., Thomson, Angus W.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553645/
https://ncbi.nlm.nih.gov/pubmed/27477490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneph.2016.108
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