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Roles of mTOR complexes in the kidney: implications for renal disease and transplantation
The mTOR pathway has a central role in the regulation of cell metabolism, growth and proliferation. Studies involving selective gene targeting of mTOR complexes (mTORC1 and mTORC2) in renal cell populations and/or pharmacologic mTOR inhibition have revealed important roles of mTOR in podocyte homeos...
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| Published in: | Nat Rev Nephrol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6553645/ https://ncbi.nlm.nih.gov/pubmed/27477490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneph.2016.108 |
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