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Rapamycin and mTOR kinase inhibitors
Mammalian target of rapamycin (mTOR) is a protein kinase that controls cell growth, proliferation, and survival. mTOR signaling is often upregulated in cancer and there is great interest in developing drugs that target this enzyme. Rapamycin and its analogs bind to a domain separate from the catalyt...
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| Glavni autori: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Springer-Verlag
2008
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2698317/ https://ncbi.nlm.nih.gov/pubmed/19568796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12154-008-0003-5 |
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