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Rapamycin and mTOR kinase inhibitors

Mammalian target of rapamycin (mTOR) is a protein kinase that controls cell growth, proliferation, and survival. mTOR signaling is often upregulated in cancer and there is great interest in developing drugs that target this enzyme. Rapamycin and its analogs bind to a domain separate from the catalyt...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ballou, Lisa M., Lin, Richard Z.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer-Verlag 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698317/
https://ncbi.nlm.nih.gov/pubmed/19568796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12154-008-0003-5
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