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mTOR signaling in growth control and disease

The mammalian target of rapamycin (mTOR) signaling pathway senses and integrates a variety of environmental cues to regulate organismal growth and homeostasis. The pathway regulates many major cellular processes and is implicated in an increasing number of pathological conditions, including cancer,...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Laplante, Mathieu, Sabatini, David M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331679/
https://ncbi.nlm.nih.gov/pubmed/22500797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.03.017
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