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mTOR signaling in growth control and disease

The mammalian target of rapamycin (mTOR) signaling pathway senses and integrates a variety of environmental cues to regulate organismal growth and homeostasis. The pathway regulates many major cellular processes and is implicated in an increasing number of pathological conditions, including cancer,...

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Detalhes bibliográficos
Main Authors: Laplante, Mathieu, Sabatini, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331679/
https://ncbi.nlm.nih.gov/pubmed/22500797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.03.017
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