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Nutrient Signaling to mTOR and Cell Growth

The mammalian target of rapamycin (mTOR) is a conserved protein kinase involved in a multitude of cellular processes including cell growth. Increased mTOR activation is observed in multiple human cancers and inhibition of mTOR has proven efficacious in numerous clinical trials. mTOR comprises two co...

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Hlavní autoři: Jewell, Jenna L., Guan, Kun-Liang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634910/
https://ncbi.nlm.nih.gov/pubmed/23465396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2013.01.004
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