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Quantitative, Multiplexed Assays for Low Abundance Proteins in Plasma by Targeted Mass Spectrometry and Stable Isotope Dilution

Biomarker discovery produces lists of candidate markers whose presence and level must be subsequently verified in serum or plasma. Verification represents a paradigm shift from unbiased discovery approaches to targeted, hypothesis-driven methods and relies upon specific, quantitative assays optimize...

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Main Authors: Keshishian, Hasmik, Addona, Terri, Burgess, Michael, Kuhn, Eric, Carr, Steven A.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435059/
https://ncbi.nlm.nih.gov/pubmed/17939991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M700354-MCP200
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