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Quantitative, Multiplexed Assays for Low Abundance Proteins in Plasma by Targeted Mass Spectrometry and Stable Isotope Dilution

Biomarker discovery produces lists of candidate markers whose presence and level must be subsequently verified in serum or plasma. Verification represents a paradigm shift from unbiased discovery approaches to targeted, hypothesis-driven methods and relies upon specific, quantitative assays optimize...

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Autores principales: Keshishian, Hasmik, Addona, Terri, Burgess, Michael, Kuhn, Eric, Carr, Steven A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435059/
https://ncbi.nlm.nih.gov/pubmed/17939991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M700354-MCP200
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