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Quantitation of DNA adducts by stable isotope dilution mass spectrometry

Exposure to endogenous and exogenous chemicals can lead to the formation of structurally modified DNA bases (DNA adducts). If not repaired, these nucleobase lesions can cause polymerase errors during DNA replication, leading to heritable mutations potentially contributing to the development of cance...

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Dettagli Bibliografici
Autori principali: Tretyakova, Natalia, Goggin, Melissa, Janis, Gregory
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495176/
https://ncbi.nlm.nih.gov/pubmed/22827593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx3002548
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