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Capture of the volatile carbonyl metabolite of flecainide on 2,4-dinitrophenylhydrazine cartridge for quantitation by stable-isotope dilution mass spectrometry coupled with chromatography

Carbonyl compounds are common byproducts of many metabolic processes. These volatile chemical entities are usually derivatized before mass spectrometric analysis to enhance the sensitivity of their detections. The classically used reagent for this purpose is 2,4-dinitrophenylhydrazine (DNPH) that fo...

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Библиографические подробности
Главные авторы: Prokai, Laszlo, Szarka, Szabolcs, Wang, Xiaoli, Prokai-Tatrai, Katalin
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303990/
https://ncbi.nlm.nih.gov/pubmed/22342210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2012.01.067
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