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Relative quantitation of protein nitration by liquid chromatography–mass spectrometry using isotope-coded dimethyl labeling and chemoprecipitation
Protein nitration has been recognized as an important biomarker for nitroxidative stress associated with various diseases. While identification of protein targets for nitration is important, its quantitative profiling also is necessary to understand the biological impact of this low-abundance posttr...
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Autori principali: | , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2012
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3482478/ https://ncbi.nlm.nih.gov/pubmed/22285050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2011.12.100 |
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