Quantitative analysis of WRN exonuclease activity by isotope dilution mass spectrometry

Werner syndrome is a disorder characterized by a premature aging phenotype. The disease is caused by mutations in the WRN gene which encodes a DNA helicase/exonuclease which is involved in multiple aspects of DNA metabolism. Current methods mostly rely on radiometric techniques to assess WRN exonucl...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Mech Ageing Dev
Autori principali: Mangerich, Aswin, Veith, Sebastian, Popp, Oliver, Fahrer, Jörg, Martello, Rita, Bohr, Vilhelm A., Bürkle, Alexander
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586252/
https://ncbi.nlm.nih.gov/pubmed/22766507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2012.06.005
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi