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Site-specific non-covalent interaction of the biopolymer poly(ADP-ribose) with the Werner syndrome protein regulates protein functions

Werner syndrome is a premature aging disorder that is caused by defects in the Werner protein (WRN). WRN is a member of the RecQ helicase family and possesses helicase and exonuclease activities. It is involved in various aspects of DNA metabolism such as DNA repair, telomere maintenance, and replic...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Popp, Oliver, Veith, Sebastian, Fahrer, Jörg, Bohr, Vilhelm A., Bürkle, Alexander, Mangerich, Aswin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549037/
https://ncbi.nlm.nih.gov/pubmed/23082994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300363g
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