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Site-specific non-covalent interaction of the biopolymer poly(ADP-ribose) with the Werner syndrome protein regulates protein functions
Werner syndrome is a premature aging disorder that is caused by defects in the Werner protein (WRN). WRN is a member of the RecQ helicase family and possesses helicase and exonuclease activities. It is involved in various aspects of DNA metabolism such as DNA repair, telomere maintenance, and replic...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3549037/ https://ncbi.nlm.nih.gov/pubmed/23082994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300363g |
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