Central Role for the Werner Syndrome Protein/Poly(ADP-Ribose) Polymerase 1 Complex in the Poly(ADP-Ribosyl)ation Pathway after DNA Damage

A defect in the Werner syndrome protein (WRN) leads to the premature aging disease Werner syndrome (WS). Hallmark features of cells derived from WS patients include genomic instability and hypersensitivity to certain DNA-damaging agents. WRN contains a highly conserved region, the RecQ conserved dom...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: von Kobbe, Cayetano, Harrigan, Jeanine A., May, Alfred, Opresko, Patricia L., Dawut, Lale, Cheng, Wen-Hsing, Bohr, Vilhelm A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2003
Gaiak:
Cell Growth and Development
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC262662/
https://ncbi.nlm.nih.gov/pubmed/14612404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.23.8601-8613.2003
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