Central Role for the Werner Syndrome Protein/Poly(ADP-Ribose) Polymerase 1 Complex in the Poly(ADP-Ribosyl)ation Pathway after DNA Damage

A defect in the Werner syndrome protein (WRN) leads to the premature aging disease Werner syndrome (WS). Hallmark features of cells derived from WS patients include genomic instability and hypersensitivity to certain DNA-damaging agents. WRN contains a highly conserved region, the RecQ conserved dom...

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Εκδόθηκε σε:	Mol Cell Biol
Κύριοι συγγραφείς:	von Kobbe, Cayetano, Harrigan, Jeanine A., May, Alfred, Opresko, Patricia L., Dawut, Lale, Cheng, Wen-Hsing, Bohr, Vilhelm A.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Taylor & Francis 2003
Θέματα:	Cell Growth and Development
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262662/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14612404/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.23.8601-8613.2003
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