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The Bloom’s and Werner’s syndrome proteins are DNA structure-specific helicases

BLM and WRN, the products of the Bloom’s and Werner’s syndrome genes, are members of the RecQ family of DNA helicases. Although both have been shown previously to unwind simple, partial duplex DNA substrates with 3′→5′ polarity, little is known about the structural features of DNA that determine the...

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Detalhes bibliográficos
Main Authors: Mohaghegh, Payam, Karow, Julia K., Brosh Jr, Robert M., Bohr, Vilhelm A., Hickson, Ian D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55766/
https://ncbi.nlm.nih.gov/pubmed/11433031
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