The DNA Helicase Activity of BLM Is Necessary for the Correction of the Genomic Instability of Bloom Syndrome Cells

Bloom syndrome (BS) is a rare autosomal recessive disorder characterized by growth deficiency, immunodeficiency, genomic instability, and the early development of cancers of many types. BLM, the protein encoded by BLM, the gene mutated in BS, is localized in nuclear foci and absent from BS cells. BL...

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Pubblicato in:	Mol Biol Cell
Autori principali:	Neff, Norma F., Ellis, Nathan A., Ye, Tian Zhang, Noonan, James, Huang, Kelly, Sanz, Maureen, Proytcheva, Maria
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Cell Biology 1999
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25194/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10069810/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.10.3.665
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