The DNA Helicase Activity of BLM Is Necessary for the Correction of the Genomic Instability of Bloom Syndrome Cells

Bloom syndrome (BS) is a rare autosomal recessive disorder characterized by growth deficiency, immunodeficiency, genomic instability, and the early development of cancers of many types. BLM, the protein encoded by BLM, the gene mutated in BS, is localized in nuclear foci and absent from BS cells. BL...

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發表在:	Mol Biol Cell
Principais autores:	Neff, Norma F., Ellis, Nathan A., Ye, Tian Zhang, Noonan, James, Huang, Kelly, Sanz, Maureen, Proytcheva, Maria
格式:	Artigo
語言:	Inglês
出版:	American Society for Cell Biology 1999
主題:	Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25194/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10069810/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.10.3.665
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