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The DNA Helicase Activity of BLM Is Necessary for the Correction of the Genomic Instability of Bloom Syndrome Cells

Bloom syndrome (BS) is a rare autosomal recessive disorder characterized by growth deficiency, immunodeficiency, genomic instability, and the early development of cancers of many types. BLM, the protein encoded by BLM, the gene mutated in BS, is localized in nuclear foci and absent from BS cells. BL...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Neff, Norma F., Ellis, Nathan A., Ye, Tian Zhang, Noonan, James, Huang, Kelly, Sanz, Maureen, Proytcheva, Maria
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The American Society for Cell Biology 1999
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC25194/
https://ncbi.nlm.nih.gov/pubmed/10069810
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