Differential and Concordant Roles for Poly(ADP-Ribose) Polymerase 1 and Poly(ADP-Ribose) in Regulating WRN and RECQL5 Activities

Poly(ADP-ribose) (PAR) polymerase 1 (PARP1) catalyzes the poly(ADP-ribosyl)ation (PARylation) of proteins, a posttranslational modification which forms the nucleic acid-like polymer PAR. PARP1 and PAR are integral players in the early DNA damage response, since PARylation orchestrates the recruitmen...

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Publicado no:Mol Cell Biol
Main Authors: Khadka, Prabhat, Hsu, Joseph K., Veith, Sebastian, Tadokoro, Takashi, Shamanna, Raghavendra A., Mangerich, Aswin, Croteau, Deborah L., Bohr, Vilhelm A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628069/
https://ncbi.nlm.nih.gov/pubmed/26391948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00427-15
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