TCDD decreases ATP levels and increases reactive oxygen production through changes in mitochondrial F(0)F(1)-ATP synthase and ubiquinone

by Shertzer, Howard G., Genter, Mary Beth, Shen, Dongxiao, Nebert, Daniel W., Chen, Ying, Dalton, Timothy P.
Published 2006

Oral N-acetylcysteine rescues lethality of hepatocyte-specific Gclc knockout mice providing a model for hepatic cirrhosis

by Chen, Ying, Johansson, Elisabet, Yang, Yi, Miller, Marian L., Shen, Dongxiao, Orlicky, David J., Shertzer, Howard G., Vasiliou, Vasilis, Nebert, Daniel W., Dalton, Timothy P.
Published 2010

MicroRNA-942 mediates hepatic stellate cell activation by regulating BAMBI expression in human liver fibrosis

by Tao, Le, Xue, Dongying, Shen, Dongxiao, Ma, Wenting, Zhang, Jie, Wang, Xuefei, Zhang, Wei, Wu, Liu, Pan, Kai, Yang, Yanqin, Nwosu, Zeribe C., Dooley, Steven, Seki, Ekihiro, Liu, Cheng
Published in Arch Toxicol (2018)

Aortic Aneurysm Generation in Mice with Targeted Deletion of Integrin Linked Kinase (ILK) in Vascular Smooth Muscle Cells

by Shen, Dongxiao, Li, Jian, Lepore, John J., Anderson, Thomas J.T., Sinha, Sumita, Lin, Alexander Y., Cheng, Lan, Cohen, Ethan David, Roberts, Jesse D., Dedhar, Shoukat, Parmacek, Michael S., Gerszten, Robert E.
Published 2011

The Genetic Architecture of the Cardiovascular Risk Proteome

by Benson, Mark D., Yang, Qiong, Ngo, Debby, Zhu, Yineng, Shen, Dongxiao, Farrell, Laurie A., Sinha, Sumita, Keyes, Michelle J., Vasan, Ramachandran S., Larson, Martin G., Smith, J. Gustav, Wang, Thomas J., Gerszten, Robert E.
Published in Circulation (2017)

Interferon-γ and the Interferon-Inducible Chemokine, CXCL10, Protect Against Aneurysm Formation and Rupture

by King, Victoria L., Lin, Alexander Y., Kristo, Fjoralba, Anderson, Thomas J.T., Ahluwalia, Neil, Hardy, Gregory, Owens, A. Phillip, Howatt, Deborah A., Shen, Dongxiao, Tager, Andrew M., Luster, Andrew D., Daugherty, Alan, Gerszten, Robert E.
Published 2009

IKKβ regulates essential functions of the vascular endothelium through kinase-dependent and -independent pathways

by Ashida, Noboru, SenBanerjee, Sucharita, Kodama, Shohta, Foo, Shi Yin, Coggins, Matthew, Spencer, Joel A., Zamiri, Parisa, Shen, Dongxiao, Li, Ling, Sciuto, Tracey, Dvorak, Ann, Gerszten, Robert E., Lin, Charles P., Karin, Michael, Rosenzweig, Anthony
Published 2011

A pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease

by Addona, Terri A, Shi, Xu, Keshishian, Hasmik, Mani, D R, Burgess, Michael, Gillette, Michael A, Clauser, Karl R, Shen, Dongxiao, Lewis, Gregory D, Farrell, Laurie A, Fifer, Michael A, Sabatine, Marc S, Gerszten, Robert E, Carr, Steven A
Published 2011

Aptamer-Based Proteomic Profiling Reveals Novel Candidate Biomarkers and Pathways in Cardiovascular Disease

by Ngo, Debby, Sinha, Sumita, Shen, Dongxiao, Kuhn, Eric W., Keyes, Michelle J., Shi, Xu, Benson, Mark D., O’ Sullivan, John F., Keshishian, Hasmik, Farrell, Laurie A., Fifer, Michael A., Vasan, Ramachandran S., Sabatine, Marc S., Larson, Martin G., Carr, Steven A., Wang, Thomas J., Gerszten, Robert E.
Published in Circulation (2016)

Profiling of the plasma proteome across different stages of human heart failure

by Egerstedt, Anna, Berntsson, John, Smith, Maya Landenhed, Gidlöf, Olof, Nilsson, Roland, Benson, Mark, Wells, Quinn S., Celik, Selvi, Lejonberg, Carl, Farrell, Laurie, Sinha, Sumita, Shen, Dongxiao, Lundgren, Jakob, Rådegran, Göran, Ngo, Debby, Engström, Gunnar, Yang, Qiong, Wang, Thomas J., Gerszten, Robert E., Smith, J. Gustav
Published in Nat Commun (2019)

Metabolite Profiling Identifies Pathways Associated with Metabolic Risk in Humans

by Cheng, Susan, Rhee, Eugene P., Larson, Martin G., Lewis, Gregory D., McCabe, Elizabeth L., Shen, Dongxiao, Palma, Melinda J., Roberts, Lee D., Dejam, Andre, Souza, Amanda L., Deik, Amy A., Magnusson, Martin, Fox, Caroline S., O'Donnell, Christopher J., Vasan, Ramachandran S., Melander, Olle, Clish, Clary B., Gerszten, Robert E., Wang, Thomas J.
Published 2012

Proteomic Profiling in Biracial Cohorts Implicates DC-SIGN as a Mediator of Genetic Risk in COVID-19

by Katz, Daniel H., Tahir, Usman A., Ngo, Debby, Benson, Mark D., Bick, Alexander G., Pampana, Akhil, Gao, Yan, Keyes, Michelle J., Correa, Adolfo, Sinha, Sumita, Shen, Dongxiao, Yang, Qiong, Robbins, Jeremy M., Chen, Zsu-Zsu, Cruz, Daniel E., Peterson, Bennet, Natarajan, Pradeep, Vasan, Ramachandran S., Smith, Gustav, Wang, Thomas J., Gerszten, Robert E.
Published in medRxiv (2020)

A Genome-Wide Association Study of the Human Metabolome in a Community-Based Cohort

by Rhee, Eugene P., Ho, Jennifer E., Chen, Ming-Huei, Shen, Dongxiao, Cheng, Susan, Larson, Martin G., Ghorbani, Anahita, Shi, Xu, Helenius, Iiro T., O’Donnell, Christopher J., Souza, Amanda L., Deik, Amy, Pierce, Kerry A., Bullock, Kevin, Walford, Geoffrey A., Vasan, Ramachandran S., Florez, Jose C., Clish, Clary, Yeh, J.-R. Joanna, Wang, Thomas J., Gerszten, Robert E.
Published 2013

Aptamer-Based Proteomic Platform Identifies Novel Protein Predictors of Incident Heart Failure and Echocardiographic Traits

by Nayor, Matthew, Short, Meghan I., Rasheed, Humaira, Lin, Honghuang, Jonasson, Christian, Yang, Qiong, Hveem, Kristian, Felix, Janine F., Morrison, Alanna C., Wild, Philipp S., Morley, Michael P., Cappola, Thomas P., Benson, Mark D., Ngo, Debby, Sinha, Sumita, Keyes, Michelle J., Shen, Dongxiao, Wang, Thomas J., Larson, Martin G., Brumpton, Ben M., Gerszten, Robert E., Omland, Torbjørn, Vasan, Ramachandran S.
Published in Circ Heart Fail (2020)

Circulating testican-2 is a podocyte-derived marker of kidney health

by Ngo, Debby, Wen, Donghai, Gao, Yan, Keyes, Michelle J., Drury, Erika R., Katz, Dan H., Benson, Mark D., Sinha, Sumita, Shen, Dongxiao, Farrell, Laurie A., Peterson, Bennet D., Friedman, David J., Elmariah, Sammy, Young, Bessie A., Smith, J. Gustav, Yang, Qiong, Vasan, Ramachandran S., Larson, Martin G., Correa, Adolfo, Humphreys, Benjamin D., Wang, Thomas J., Pollak, Martin R., Wilson, James G., Gerszten, Robert E., Rhee, Eugene P.
Published in Proc Natl Acad Sci U S A (2020)

Proteomic profiling reveals biomarkers and pathways in type 2 diabetes risk

by Ngo, Debby, Benson, Mark D., Long, Jonathan Z., Chen, Zsu-Zsu, Wang, Ruiqi, Nath, Anjali K., Keyes, Michelle J., Shen, Dongxiao, Sinha, Sumita, Kuhn, Eric, Morningstar, Jordan E., Shi, Xu, Peterson, Bennet D., Chan, Christopher, Katz, Daniel H., Tahir, Usman A., Farrell, Laurie A., Melander, Olle, Mosley, Jonathan D., Carr, Steven A., Vasan, Ramachandran S., Larson, Martin G., Smith, J. Gustav, Wang, Thomas J., Yang, Qiong, Gerszten, Robert E.
Published in JCI Insight (2021)