Aptamer-Based Proteomic Platform Identifies Novel Protein Predictors of Incident Heart Failure and Echocardiographic Traits

BACKGROUND: We used a large-scale, high-throughput DNA aptamer-based discovery proteomic platform to identify circulating biomarkers of cardiac remodeling and incident heart failure (HF) in community-dwelling individuals. METHODS: We evaluated 1895 Framingham Heart Study (FHS) participants (age 55±1...

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Vydáno v:Circ Heart Fail
Hlavní autoři: Nayor, Matthew, Short, Meghan I., Rasheed, Humaira, Lin, Honghuang, Jonasson, Christian, Yang, Qiong, Hveem, Kristian, Felix, Janine F., Morrison, Alanna C., Wild, Philipp S., Morley, Michael P., Cappola, Thomas P., Benson, Mark D., Ngo, Debby, Sinha, Sumita, Keyes, Michelle J., Shen, Dongxiao, Wang, Thomas J., Larson, Martin G., Brumpton, Ben M., Gerszten, Robert E., Omland, Torbjørn, Vasan, Ramachandran S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7236427/
https://ncbi.nlm.nih.gov/pubmed/32408813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.119.006749
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