Aptamer-Based Proteomic Profiling Reveals Novel Candidate Biomarkers and Pathways in Cardiovascular Disease

BACKGROUND: Single-stranded DNA aptamers are oligonucleotides of approximately 50 base pairs in length selected for their ability to bind proteins with high specificity and affinity. Emerging DNA aptamer-based technologies may address limitations of existing proteomic techniques, including low sampl...

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Publicado no:Circulation
Main Authors: Ngo, Debby, Sinha, Sumita, Shen, Dongxiao, Kuhn, Eric W., Keyes, Michelle J., Shi, Xu, Benson, Mark D., O’ Sullivan, John F., Keshishian, Hasmik, Farrell, Laurie A., Fifer, Michael A., Vasan, Ramachandran S., Sabatine, Marc S., Larson, Martin G., Carr, Steven A., Wang, Thomas J., Gerszten, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963294/
https://ncbi.nlm.nih.gov/pubmed/27444932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.116.021803
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