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In silico selection of RNA aptamers

In vitro selection of RNA aptamers that bind to a specific ligand usually begins with a random pool of RNA sequences. We propose a computational approach for designing a starting pool of RNA sequences for the selection of RNA aptamers for specific analyte binding. Our approach consists of three step...

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Detalles Bibliográficos
Main Authors: Chushak, Yaroslav, Stone, Morley O.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709588/
https://ncbi.nlm.nih.gov/pubmed/19465396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp408
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