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A Genome-Wide Association Study of the Human Metabolome in a Community-Based Cohort

Because metabolites are hypothesized to play key roles as markers and effectors of cardio-metabolic diseases, recent studies have sought to annotate the genetic determinants of circulating metabolite levels. We report a genome-wide association study (GWAS) of 217 plasma metabolites, including >10...

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Detalhes bibliográficos
Main Authors: Rhee, Eugene P., Ho, Jennifer E., Chen, Ming-Huei, Shen, Dongxiao, Cheng, Susan, Larson, Martin G., Ghorbani, Anahita, Shi, Xu, Helenius, Iiro T., O’Donnell, Christopher J., Souza, Amanda L., Deik, Amy, Pierce, Kerry A., Bullock, Kevin, Walford, Geoffrey A., Vasan, Ramachandran S., Florez, Jose C., Clish, Clary, Yeh, J.-R. Joanna, Wang, Thomas J., Gerszten, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973158/
https://ncbi.nlm.nih.gov/pubmed/23823483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.06.013
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