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Interferon-γ and the Interferon-Inducible Chemokine, CXCL10, Protect Against Aneurysm Formation and Rupture

BACKGROUND: Vascular disease can manifest as stenotic plaques or ectatic aneurysms, though the mechanisms culminating in these divergent disease manifestations remain poorly understood. T helper type 1 (Th1) cytokines, including interferon (IFN)-γ and CXCL10, have been strongly implicated in atheros...

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Bibliografiske detaljer
Main Authors: King, Victoria L., Lin, Alexander Y., Kristo, Fjoralba, Anderson, Thomas J.T., Ahluwalia, Neil, Hardy, Gregory, Owens, A. Phillip, Howatt, Deborah A., Shen, Dongxiao, Tager, Andrew M., Luster, Andrew D., Daugherty, Alan, Gerszten, Robert E.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765043/
https://ncbi.nlm.nih.gov/pubmed/19139386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.785949
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