Interferon-γ and the Interferon-Inducible Chemokine, CXCL10, Protect Against Aneurysm Formation and Rupture

BACKGROUND: Vascular disease can manifest as stenotic plaques or ectatic aneurysms, though the mechanisms culminating in these divergent disease manifestations remain poorly understood. T helper type 1 (Th1) cytokines, including interferon (IFN)-γ and CXCL10, have been strongly implicated in atheros...

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Hlavní autoři: King, Victoria L., Lin, Alexander Y., Kristo, Fjoralba, Anderson, Thomas J.T., Ahluwalia, Neil, Hardy, Gregory, Owens, A. Phillip, Howatt, Deborah A., Shen, Dongxiao, Tager, Andrew M., Luster, Andrew D., Daugherty, Alan, Gerszten, Robert E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765043/
https://ncbi.nlm.nih.gov/pubmed/19139386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.785949
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